KMID : 0360220210620060769
|
|
Journal of the Korean Ophthalmological Society 2021 Volume.62 No. 6 p.769 ~ p.776
|
|
Microvasculature and Nerve Fiber Layer-Ganglion Cell Inner Plexiform Layer Thickness in Type 2 Diabetes
|
|
Seo Jin-Seok
Cho Yong-Wun Seo Seong-Wook Kim Seong-Jae Chung In-Young Yoo Woong-Sun
|
|
Abstract
|
|
|
Purpose: To investigate thickness of the nerve fiber layer-ganglion cell inner plexiform layer (NFL-GCIPL) complex and vessel density of the superficial and deep retinal vessels and choriocapillaris using swept source optical coherence tomography (SS-OCT) and angiography (OCTA) in type 2 diabetic patients without diabetic retinopathy (DR).
Methods: Sixty-four eyes of type 2 diabetic patients without DR were included. A control group of 54 eyes without diabetes was also recruited. All patients underwent multimodal imaging evaluation using SS-OCT and OCTA.
Results: Vessel density of the superficial and deep retinal vessels was not different between the study and control groups. A significant decrease in NFL-GCIPL complex thickness was observed in the study group compared to the control group. NFL-GCIPL thickness of the macula decreased with increased duration of diabetes.
Conclusions: These results suggest that neurodegeneration might be an early change in the development of DR.
|
|
KEYWORD
|
|
Diabetic retinopathy, Neurodegeneration, Optical coherence tomography, Optical coherence tomographic angiography
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|